During the process of developing new drugs, the stability, processability, look, and performance of the product can all be impacted by the physical and chemical characteristics of pharmaceutical materials. To guarantee the caliber, security, and effectiveness of pharmaceutical products, Protheragen-ING provides an extensive array of chemistry-physical testing services.
We have extensive experience with a range of product types, from raw materials to active pharmaceutical ingredients, and can accommodate virtually any product type. We are dedicated to providing reliable and quick findings to support your drug development and manufacturing operations, whether you require routine testing, method development, or manufacturing services.
Our Testing Capabilities
Protheragen-ING performs a range of physical tests to evaluate the physical properties and characteristics of pharmaceutical products, including dissolution testing, particle size analysis, viscosity measurement, density determination, friability testing, hardness testing, and moisture content determination. Our physical testing services help evaluate drug release profiles, formulation stability, solid-state characterization, and overall product quality.
Protheragen-ING utilizes a variety of analytical methods to assess the chemical composition, purity, and stability of pharmaceuticals, including high-performance liquid chromatography (HPLC), gas chromatography (GC), infrared spectroscopy (IR), mass spectrometry (MS), and nuclear magnetic resonance (NMR) spectroscopy. Our chemical analysis services include identification and quantification of active pharmaceutical ingredients (APIs), impurities, degradation products and excipients.
| Fourier transform infrared and near infrared absorption spectra (FTIR, NIR) |
- Fingerprinting of known scans.
- Identification of functional groups within molecular structures.
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| Ultraviolet-visible absorption spectroscopy (UV/VIS) |
- Determination of characteristic absorption patterns.
- For qualitative testing, quantitative calculations and kinetic analysis.
- Measurement of molar extinction coefficient (MEC).
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| Carbon, Hydrogen and Nitrogen Analysis (CHN Elemental Analysis) |
- Determination of mass fraction of carbon, hydrogen and nitrogen content.
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| Metals Testing (ICP-MS) |
- Trace quantification of most elements in liquids and solids.
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| Mass spectrometry (GC-MS, HPLC-MS) |
- Measurement of the mass of parent compounds or daughter ions.
- Confirmation of molecular weight.
- Assessment of unknown purity.
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| NMR spectroscopy |
- Capable of qNMR and 3D-NMR.
- Solid state characterization: crystal polymorphism, ID, limits and impurities.
- Compound library enables high-throughput QC, protein-ligand NMR binding assays.
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Comprehensive Testing Services
Our range of services covers the entire spectrum of chemical-physical testing of pharmaceuticals. In addition to performing standardized analytical procedures, Protheragen-ING can also provide procedure development and validation according to customer-specific requirements.
Sample Types
Protheragen-ING has experience with a wide range of sample types, including:
- Raw materials
- Development materials
- Intermediate in-process materials
- Active pharmaceutical ingredients
- Stability study samples
- Unknowns for identification or confirmation
Protheragen-ING's state-of-the-art laboratory facilities, team of experienced scientists, and compliance with regulatory guidelines make us a trusted partner for pharmaceutical companies looking for reliable testing solutions.
Contact us today to discuss your pharmaceutical chemistry and physical testing requirements and learn how we can help you ensure the quality and safety of your pharmaceutical products. We will respond within 2-4 working days.
