Microencapsulation Drug Delivery System Services

Microencapsulation technology refers to the technology of using natural or synthetic polymer materials or copolymers as wall materials to encapsulate solid or liquid drugs to form a microcapsule with a semi-permeable or sealed capsule membrane with a diameter in the range of 1 um to 5000 um. Formulations using microencapsulation technology are mainly antipyretic and analgesic drugs, antibiotics, peptides, contraceptives, vitamins, mineral salts, anticancer drugs, and diagnostic drugs.

Fig.1 Schematic structure of microcapsules.Fig. 1 Schematic structure of microcapsules. (Eghbal N, et al. 2022)

Protheragen-ING specializes in providing cutting-edge microencapsulation drug delivery system (DDS) services. Our team of experts utilizes state-of-the-art technology and industry best practices to develop innovative drug delivery solutions that enhance the efficacy, stability, and bioavailability of pharmaceutical compounds.

Purpose of Drug Microencapsulation

Composition of Microencapsulation DDS

Encapsulated core material and additives

In our formulation development, the capsule core substance can be a single solid or liquid drug or a mixture of solid-liquid, liquid-liquid, solid-solid, etc. This includes additives such as stabilizers, diluents, blockers, etc. in addition to the main drug to improve the quality of microencapsulation.

Capsule wall material

Our general requirements for the selection of capsule wall material include stable nature; suitable release rate; non-toxic, non-irritant; can be matched with the drug, does not affect the pharmacological effect of the drug and content determination; with viscosity, penetration, hydrophilicity, solubility, degradation and so on in line with the requirements.

Usually, a wall material is difficult to have the above properties at the same time, so we often use several wall materials.

Fig.2 Technologic process of probiotic bacteria microencapsulation.

Our Microencapsulation DDS Services

Technical Methods of Microencapsulation

Spray drying method, spray freezing method, air suspension method, electrostatic binding method, vacuum evaporation deposition method, etc.

Oil phase separation method, water phase separation method, melting separation method, complex phase emulsion method, extrusion method, etc.

Interfacial polymerization method, radiation encapsulation method, molecular encapsulation method, in situ polymerization method, etc.

To learn more about our services or to discuss your specific requirements, please contact our team.


  1. Eghbal N, et al. (2022). "Microencapsulation of Natural Food Antimicrobials: Methods and Applications." Appl. Sci, 12(8), 3837.


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