Headspace Gas Analysis for Pharmaceutical Packaging

In the pharmaceutical industry, the quality of packaging plays a vital role in the protection and stability of pharmaceuticals. Headspace analysis technology is a method widely used in pharmaceutical packaging quality control to evaluate the content of gases such as oxygen and carbon dioxide inside pharmaceutical packaging. This technology can monitor the gas environment inside drug packaging in real time and accurately, thereby evaluating the barrier performance of the packaging and the storage status of the drug, and providing key information for the quality and stability of the drug.

Protheragen-ING understands the critical importance of ensuring the quality and integrity of pharmaceutical products throughout their life cycle. Our advanced headspace gas analysis solutions provide accurate and reliable data, allowing you to maintain the highest safety and effectiveness standards for pharmaceutical packaging.

Customized Analysis Services

Fig.1 Headspace Gas Analysis for Pharmaceutical Packaging

Protheragen-ING provides comprehensive headspace gas analysis services designed to meet the pharmaceutical industry's quality control needs for pharmaceutical packaging. Utilizing state-of-the-art equipment and industry-recognized methodologies, our expert team can provide customized analytical solutions based on your specific requirements.

We use a variety of analytical methods to evaluate headspace gases in pharmaceutical packaging, including gas chromatography-mass spectrometry (GC-MS), gas chromatography-flame ionization detector (GC-FID), and gas chromatography-thermal conductivity detector (GC-TCD), etc. These methods can effectively separate and quantify gas components in the headspace, including volatile organic compounds (VOCs), moisture content, oxygen content, carbon dioxide content, and other possible impurities.

To ensure the accuracy and reliability of analysis, we are equipped with advanced analytical instruments and equipment. These instruments provide high sensitivity, high resolution, and reliable performance to accurately detect and quantify trace gas components in the head space.

Professional Analysis Technology

Our technical team is skilled in a variety of analytical techniques to accurately extract and analyze headspace gases, including:

Based on the characteristics and requirements of pharmaceutical packaging, we can select appropriate technologies to effectively capture and analyze headspace gas and provide reliable results and interpretations.

Fig.2 The laboratory set up of headspace gas analysis.Fig. 1 The laboratory set up of headspace gas analysis. (Rovira D, et al. 2019)

Applications of Our Analytics Services

By partnering with us, you gain access to reliable analytical data, regulatory compliance, and the peace of mind that comes from knowing your packaging systems meet the highest industry standards. Contact us today to discuss your specific requirements and how we can support your pharmaceutical packaging analysis needs.


  1. Rovira MD, et al. (2019). "Respiration Rate and Shelf-life Study of Crotalaria Longirostrata (Chipilín)." Journal of Food Measurement and Characterization, 13, 3025-3032.


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