Soft Capsules

Fig.1 Soft gelatin capsules containing oily medications and nutritional supplements.

The soft capsule is widely used in the pharmaceutical industry drug dosage form, that is, a certain amount of liquid drugs directly encapsulated, or solid drugs dissolved or dispersed in a suitable excipient prepared into a solution, suspension, emulsion, or semi-solid, sealed in a soft capsule made of capsule material. This dosage form is mostly applied to small dosages, water-insoluble, light-sensitive, unstable to moisture and heat, and easily oxidized and volatile drugs.

As a specialized pharmaceutical R&D and manufacturing company, Protheragen-ING is committed to providing its customers with high-quality, innovative soft gel solutions. Whether you want to develop a new product or improve an existing formulation, our team has the experience and expertise to meet your needs.

Benefits of Soft Capsules

Formulation of Soft Capsules

Our soft capsule development services cover a wide range of drug formulations. We will select the appropriate drug carrier, solvent, and excipients based on your drug properties and objectives to ensure the stability and bioavailability of the drug in the soft capsule.

A soft capsule consists of two main prescriptions: the capsule shell and the content.

Shell Prescription

The shell of the soft capsule is usually made of gelatin or vegetable cellulose. Commonly used excipients for the capsule shell include gelatin, plasticizers, water, coloring agents, opacifiers, aromatics, preservatives, etc.

Content Prescription

Most of the contents of soft gelatin capsules are liquid substances, such as oily drugs, drug solutions, suspensions, or emulsions.

Content Prescription Examples
Base oils Vegetable oils, mono-diglycerides of caprylic acid, etc.
Aqueous base Polyethylene glycol
Antioxidants Butylated hydroxytoluene (BHT), tertiary butylhydroquinone (TBHQ), etc.
Suspension aid Beeswax, hydrogenated vegetable oil, etc.
Hydrophilic surfactants (HLB value >10) Polyoxyethylene castor oil, polyoxyethylene hydrogenated castor oil, etc.
Lipophilic surfactants (HLB value less than 10) Polyoxyethylene lauric acid, polyoxyethylene stearic acid, etc.

Types of Soft Capsules

Our soft capsule development services cover a wide range of applications. We can develop soft capsules for pharmaceuticals, dietary supplements, cosmetic formulations, and more. Whether you need oil-based, water-based, or combination soft capsules, we have the expertise to create the perfect solution for your product.

Fig.2 Soft Capsules.

We also can develop functional soft capsules, including but not limited to the following:

Soft capsule Manufacturing Process

Our soft capsule development services cover the entire process from formulation development to final production. We strictly follow international quality standards and specifications to ensure product safety, stability, and efficacy. Our manufacturing process includes:

(1) Drug formulation development and optimization.

(2) Raw material procurement and quality control.

(3) Soft capsule shell manufacturing.

(4) Soft capsule filling and sealing.

(5) Quality evaluation of soft capsules

(6) Soft capsule packaging and labeling.

If you are interested in our soft capsule development services or have any questions, please feel free to contact us. We look forward to providing you with quality services and realizing your drug development goals.


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Sunday : 9.30 AM–1.00 PM
Holidays: Closed

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