Syrup Development Services

Fig.1 Syrup Development Services

The pharmaceutical syrup is a nearly saturated aqueous solution of a dissolved medicinal substance or drug usually used for oral administration. It can be said that it is actually used as a vehicle for the drug. Syrups are widely used as the preferred dosage form in the pharmaceutical industry to deliver drugs in a convenient and palatable form for several reasons, including ease of administration, dosage accuracy, and improved patient compliance, especially in pediatric and geriatric populations.

Pharmaceutical syrup development services play a vital role in the formulation and production of liquid medicines. Protheragen-ING offers a one-stop shop for syrup development to meet all your syrup needs, covering a range of projects involving syrup formulation development and dosage form optimization.

Advantages of Syrups

Common Ingredients in Medicinal Syrups

In addition to water, medicated syrups may contain the following ingredients:

Ingredient Uses Common
Pharmaceutically active ingredients (APIs) The main drug or therapeutic agent that provides the desired effect. It can be a single drug or a combination of drugs.
Sweetener Improve flavor and palatability. Sucrose, fructose, sorbitol and artificial sweeteners.
Flavorings Enhance flavor and mask the bitter or unpleasant taste of the active ingredient. Natural or artificial flavors such as fruit extracts, vanillin, or peppermint.
Preservative Prevent the growth of microorganisms and extend their shelf life. Benzoic acid, sorbic acid, sodium benzoate or parabens.
Stabilizers and thickeners Maintains the uniformity and consistency of the syrup. Cellulose derivatives, xanthan gum or astragalus gum.

Syrup Preparation Process

1. Weighing and measuring: The active ingredients, sweeteners, flavoring agents, and other additives are accurately weighed and measured according to the intended recipe.

2. Mixing: The measured ingredients are mixed in suitable containers or mixing tanks, to ensure an even distribution of the ingredients and to achieve a homogeneous mix.

3. Dissolving: Dissolving the active ingredient and other solid ingredients in a suitable solvent, usually water.

4. Filtration: The syrup mixture is filtered to remove any particulate matter or impurities that may be present.

5. Adding excipients: Once filtration is complete, additional excipients such as preservatives, stabilizers, and thickeners are added and the mixture is thoroughly blended.

6. Final Adjustments: If required, the pH, viscosity, and sweetness of the syrup can be adjusted to meet the desired specifications.

7. Packaging: The final syrup is filled into appropriate containers, such as bottles or plastic containers, and sealed to maintain product integrity.

Fig.2 Science experiment and technology.

Application of Pharmaceutical Syrups

Pharmaceutical syrups have a wide range of applications and are used to deliver various types of drugs.

Contact us today to discuss your syrup formulation development project and take the first step toward bringing your vision to life.


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