Stabilizer Excipients


Stabilizer excipients are substances that are added to drug formulations to maintain their physical and chemical stability. These excipients help preserve the effectiveness, safety, and quality of pharmaceutical products throughout their shelf life. Stabilizer excipients act by inhibiting degradation reactions, preventing physical changes such as precipitation or crystallization, and protecting the drug substance from environmental factors like light, heat, and moisture.

Subtypes of Stabilizer Excipients

Antioxidants: Antioxidants are stabilizer excipients that prevent oxidative degradation of drugs caused by exposure to oxygen. They scavenge free radicals and inhibit the formation of reactive oxygen species, thereby extending the shelf life of pharmaceutical products. Common antioxidants used in pharmaceutical formulations include ascorbic acid, sodium metabisulfite, and tocopherols.

Chelating Agents: Chelating agents are used to complex and sequester metal ions that can catalyze degradation reactions. By binding to metal ions, chelating agents prevent their involvement in oxidation, hydrolysis, and other degradation processes. Ethylenediaminetetraacetic acid (EDTA) and citric acid are commonly employed chelating agents in pharmaceutical formulations.

pH Adjusters: pH adjusters are stabilizer excipients used to maintain the desired pH range of pharmaceutical formulations. Changes in pH can trigger degradation reactions or affect drug solubility. pH adjusters such as citric acid, sodium hydroxide, and hydrochloric acid are added to ensure optimal stability and efficacy of drugs.

Humectants: Humectants are stabilizer excipients that help retain moisture and prevent drying or desiccation of pharmaceutical products. They maintain the physical integrity of formulations and prevent the loss of volatile components. Common humectants include glycerin, propylene glycol, and sorbitol.


Stabilizer excipients are essential components of drug formulations, ensuring their stability, efficacy, and safety. By preventing degradation reactions, physical changes, and loss of potency, these excipients contribute to the overall quality and longevity of pharmaceutical products. Partnering with Protheragen-ING, a reputable supplier, ensures the availability of high-quality excipients and supports the development of stable and efficacious pharmaceutical products. If you have any excipient requirements, please contact us by phone or email, and we will respond within 2-4 working days.

Cat Product Name Cas Details Chemical Structure
PIE-0005 Trehalose (for injection, Sterilized) 99-20-7 View Details APIs
PIE-0011 Histidine (for injection) 71-00-1 View Details APIs
PIE-0012 Arginine (for injection) 74-79-3 View Details APIs
PIE-0022 lecithin, from egg yolk (PL-100M) (for injection) 8057-53-2 View Details APIs
PIE-0023 lecithin, from egg yolk (PC-98T) (for injection) 8057-53-2 View Details APIs
PIE-0031 N-Vinyl-2-pyrrolidone, PVPP 9003-39-8 View Details APIs
PIE-0034 Wheat Starch 9005-25-8 View Details
PIE-0038 Hydroxypropyl methyl cellulose 9004-65-3 View Details APIs
PIE-0044 Silicone Dioxide 61790-53-2 View Details
PIE-0085 Pentetic Acid 67-43-6 View Details APIs
PIE-0110 Glycine 56-40-6 View Details APIs
PIE-0115 Camphor 76-22-2 View Details APIs
PIE-0119 Citric acid 77-92-9 View Details APIs
PIE-0120 Sodium Citrate 68-04-2 View Details APIs


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